Apple's text to speech utility, VoiceOver, is very handy to listen to any written text on your Mac, yet it feels a little limited. Take GhostReader, which offers a wide choice of languages and voices and can read any text selection.
Although the original download only comes with American English, it offers more than a dozen different voices and even so, GhostReader will let you download new languages immediately from its web site. It's a shame that you only find voices from the American and European continents, still the choice given is pretty wide.
GhostReader comes in a multi-windowed interface, which put me off a bit, yet I found it very easy to playback text, either in the Reader or simply from a selection. This last point is what I really enjoyed from the program. Select any piece of text anywhere and it will play it.
You will be able to save all your texts in iTunes for later use. GhostReader also work perfectly well with hotkeys.
Although I don't enjoy the multi-windowed interface, I believe GhostReader is a great text to speech utility with many voices and simple playback.